🧬 Precision Path

Gastrointestinal
Stromal Tumor (GIST)

Turning complexity into clarity.

Tumor Pathology
Per 5 mm² (CAP/NCCN/AJCC standard). Equivalent to ~50 HPF on older microscopes.
Surgical Assessment
Tumor rupture automatically classifies as high risk (Modified NIH Criteria, Joensuu 2008)
Molecular Profile
Determines TKI sensitivity and pathway selection

Complete Location, Size, Mitotic Rate, and Mutation to continue.

Clinical Evidence Standard Pathways follow NCCN GIST Guidelines v1.2026 and ESMO Clinical Practice Guidelines. Risk is calculated using tumor size, mitotic rate (per 5 mm²), and anatomic location per Miettinen & Lasota (2006). Mutation-specific routing includes PDGFRA D842V avapritinib and Wild-Type observation pathways. All recommendations are advisory — clinical judgment governs final decisions.